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    Hello World~

    My name is Donna aka Beadseller.

    I started browsing the internet with my service provider, Prodigy... about 10 or so years ago... no...not before the dinosaurs roamed the earth! *geez*

    Back then, the internet was limited in what it had to offer. I would also like to mention that every page opened instantly. I used the internet as a venue for research. I still use it for research, but more for shopping and selling.

    Hey! Don't laugh... I had an Adam Computer too! *humpf*

    In mid January 2005, I found Overstock... not by
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    chance mind you. A dear friend of mine had tried for months to talk me into trying Overstock. Beadwitched. Was I being stubborn? Naaa...I had a store on eBay and wanted to finish out the month before I took the leap... besides, eBay's fees were on the rise and I was on the run.

    It's January.... I would love to say that I sell more than I buy, however, that doesn't seem to be the case. So there I was, sitting on over $20,000 worth of beads and beading supplies selling them at about $2 per pack on Overstock... not taking into considera
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ion the listing fees or the paypal fees....making about 20 cents per pack. WOW.... Talk about a get rich quick scheme!

    I started listing even more... still not adjusting my prices... that was what people wanted to pay... so either make the nickel or not.... January reaped just over $500 in sales... February jumped to $1,500... March jumped even further... $2,400... April hit an all time $3K in sales....

    Then I joined the buySAFE bonding service. I thought that since I had so many valued customers, I would return some of that value to
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    them and bond my products. Fortunately.... the service was free through September 2005. But it did NOTHING... absolutely NOTHING for my sales!

    In reality... my sales plummeted! By the end of May... I felt doomed! I picked up two new customers.... and heard barely a dribble from the rest.... my sales for May were a whopping $382! Where did all my customers go?!?!? What was I doing wrong?!?!?

    With all this in mind... back in March of this year, I decided to give my own ecommerce site a try. Don't get me wrong... at first I thought it w
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    s merely a pipe dream. After all.... I paid for three years of webhosting back in March and it took until the middle of August to finally have a website up and running!

    In February, 2005, I started out with shopping around to find the least expensive hosting site. Alas, I found Ace-host.net with 5,000 MB of Disk Space, 50 GB Monthly Bandwidth, (which has been expanded to 100 GB), Unlimited MySQL Databases, eMail Accounts, FTP Accounts, Sub-Domains, and a Static IP Address included. All for only $139.50 for three years.

    If you asked m
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    e to explain the above, all I would say is, I haven't a clue what any of that really means, but I can tell you that my site never crashes. *laughing*

    Next came the HTML HELL. The last time I actually wrote any HTML was about 8 years ago, when HTML was just that.... HTML. Nothing fancy. Actually, it was pretty easy to learn. I was self taught then but the book was ohhhhhh so much thinner than the newer models!

    So, I read and researched and read and researched and read some more. I didn't get very far when I decided to see just what ha
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ing someone else create this monster would cost! Needless to say, I proceeded again with reading and researching and alas....learning everything I could to find a way to produce my own site.

    Well...If you haven't looked...my site is BEADSELLER. I purchased a template for $49 and proceeded from there. What I didn't know when I purchased the template was that it was not written in language compatible with my host. So, I managed to extract what I could from it, mainly the pretty pink bars, and forged ahead with creating my store.

    Creati
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    g a webstore really wasn't that bad... NOT!!! It was a NIGHTMARE! But again... I forged ahead. Sometime in late March I realized that I had far more products than I really wanted considering that each product had to have its own product number and be listed individually.

    Needless to say, prior to this endeavor I had considered expanding on my product line, but reconsidered. Looking at the walls of drawers of beads, I should probably try to sell what I have before I drive myself out of shop/office and HOME!

    Speaking of Late March....
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ell... after working with the same attorney for 7 years... she called me into her office to say that things were just not working out. WHAT?!? What does that mean???? How could it possibly take someone SEVEN YEARS to decide that THINGS ARE JUST NOT WORKING OUT?!?!? You would think that if things were JUST NOT WORKING OUT... that would have happened say... WEEK ONE!

    This could not have happened at a worse time! I had just taken out a mortgage on my home two months before so I could purchase beads and beading supplies! The beads and bea
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ding supplies were and are still sitting here staring at me!

    Back to the store... so... I worked diligently, day and night trying to create my webstore. I would complete umteen pages and then notice that I didn't correct the font color on the previous 10 or so pages. So... edit...edit...edit....

    Then while on my way to a special employment seminar, June 2, 2005, some crazy driver plowed into the side of my car, 2002 Hyundai Elantra. I was sitting in the passenger seat that fateful day and she hit directly behind my seat and continued
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    until she managed to take out the rear axle.

    What was she thinking??? Or better still... what was she on??? Three days later, GEICO completed the estimate of damages totaling over $4,000. I didn't even see the damages as I was taken by ambulance to the hospital.

    I am still undergoing treatment and under my doctor's care. I don't think that my neck will ever be the same. My right shoulder still hurts. I require an operation on my right knee. Fifty now feels more like seventy!

    The accident put a halt to website work. I couldn't sit fo
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    very long without severe pain. My lower back and neck were hurting all the time. I would wake up at times with very little feeling in my arms or legs. I was not fairing well at all!

    In mid July, I once again returned to working diligently on the site. I was determined to get it up and running before August 1st.

    NOTE: Determination does not necessarily mean one is going to accomplish what one sets out to accomplish!

    I still needed to install a shopping cart. I chose Paypal. This required more reading and more research... some more r
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ading and research... some crying... and more reading and more crying and more research... The word PAL in Paypal has nothing to do with the setting up of its shopping cart! I was becoming more and more frustrated... but again.... I forged ahead.

    After much deliberation and many failed attempts.... I finally weeded through the poorly written instructions and managed to get the cart to work... on ONE item. WOW.... only about 1,000 more to go! *HA* After reading and researching this phenomena, I realized that I had used the wrong cart s
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    et up and somehow managed to hook up over 100 items in much the same fashion. WRONG!

    So... after crying some more and relieving my scalp of a few swatches of hair, I once again forged ahead. I re-programmed all of the wrong items with what I hoped was the corrected shopping cart programming.

    ALAS! Low and behold... they were working! WOOOOO HOOOOO! Halleluia...Halleluia...Halleluia...Halleluia...Hall... leeee...eeee...eeee...Luuuu...ia~ Thank you... please... don't applaud... what I really need you to do is THROW MONEY!

    Now I was
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ruising... hooking up each and every individual item to this shopping cart contraption... MY PAL... my buddy... my GOD! I sent out my mass mailing to almost 350 of my regular customers announcing the GRAND OPENING OF... BEADSELLER on August 18, 2005. FREE SHIPPING offered to the first 10 completed orders!

    I picked this particular day to open because first... it was the soonest I could get the site done... and second... it happened to be my son's 29th birthday and I wanted the date to be something I would remember.

    Here I am open for
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    usiness... sitting at my computer... email open... sitting... watching... sitting... watching.... watching... sitting... NOTHING.

    Three days go by.... still...NOTHING. I feel a distinctive sinking feeling in the pit of my stomach... or maybe this feeling came from the fact that I had not moved from my chair in three days! Finally... on the fourth day... a sale!!! I might add... the shipping on this sale cost me almost as much as what was purchased! Well... not making money is why I do this right? *HA*

    Day Five... still NOTHING... the
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    it occurs to me... hmm... maybe I should review my html and see whether I bothered to enter any keywords and meta stuff.... NOTHING... *waaaaaa*

    So... I start researching again... and reading...researching and reading again... which brings me to this blog... Top Ten What? Web Site Submission....

    There are very few places that allow you to submit your website for FREE! One place I did manage to find was SUBMIT EXPRESS. Keep in mind...it is VERY TRUE that NOTHING is FREE! But at least their required link was not nearly as unsightly as
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    some!

    One of the things I have been reading about and found to be VERY TRUE.... unless you pay for the service to submit your site... don't expect to have much traffic! Which in turn means... yet another NOT RICH QUICK scheme!

    Yahoo will let you submit an url for free... but to be listed in their directory... if I remember correctly... a mere $299 a year.... WOW... only $299 a year?!?!?!? Even MSN let me submit my site for FREE! And being penny poor..... who needs to pay for the misery of increasing one's sales!?!? If I had the mone
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ....if I won the lottery... if I were independently wealthy.... ifa.... woulda.... coulda... *UGHHHH*

    Not all is lost though.

    One of the most interesting and fun things I happened upon were WebRings. WOW... these are fantastic resources. You see... after all the reading and research... everyone selling the website submission service tells you that the more places you are linked to, the more you move up in rank. Well.... while reviewing all of the webrings.... I forgot the rank issue and became extremely interested in the fact that th
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    re are literally a gillion WebRings! I was amazed with all of the RINGS that actually revolved around what I sell and what I love.... BEADS and ARTISAN JEWELRY! WOOO HOOO!

    So... even if I don't sell much... I have found that there are literally thousands of others out there in cyberspace who have huge shoulders available to cry upon. Gotta love those webring heroes and heroins!

    Well... that's quite enough for now.... if you should be reading this and happen to buy beads and beading supplies.... give me a try. Beadseller... That's me


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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