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Spam is a word with so many negative connotations, almost entirely attached to the online world. Yet today I saw something different that surprised me. As I

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

run my own business in the real world(old fashioned I know), I was out in the local area delivering fliers for our services.

I have certain rules when it come

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s to my fliers. I fold them so my logo shows on the outside, rather than blank paper. I try to be concise as possible in getting as much information to the c

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ustomer as quickly as their attention span allows. I always deliver them on a sunny day, by hand and myself. And finally, I will never drop one of my fliers

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in a letterbox with "No circulars" or "No Junk Mail" signs.

This last rule is, in my opinion, just common manners. The householder has clearly indicated they

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

don't wish to have any advertising delivered to them, and if I were to drop my flier in their box it would be more likely to upset them than get me a sale. U

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

pset people talk, and I don't want negative talk about my business.

Now, I don't consider my fliers to be junk, I present a genuine opportunity to save money

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

they are already spending anyway, but I can't go making that call on someone elses behalf.

Today I was out in the local area dropping off fliers, chatting to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

anyone who was about and carefully not stuffing the fliers in the wrong boxes when I came across a box that didn't say "No Junk Mail" or "No Circulars". It sa

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

id, in big red letters "NO SPAM" and I laughed out loud.

Spam into your regular mail box. Just yesterday I wrote an article on how the CAN SPAM act was unjus

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tly expecting people to opt out of every single spammers mail, yet here I was applying a similar principle to my own promotions. "No Junk Mail" signs are an o

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

pt out. They don't gaurantee you will get no junk mail, but from those who respect your opinion they do. generally those who take personally responsibility f

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

or your their businesses advertising WILL respect your 'opt-out' because it costs them not to. In the real world there is a cost associated with each flier I

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

drop(Cost of paper, ink and my time to distribute). Why would I waste that money on someone who is clearly not interested in what I have to offer?

There are

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

two reasons I don't consider my fliers to be 'spam'. Firstly, it is clearly identifiable. My name is on it, my logo is on it, my contact details are on it.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Now this takes a CAN SPAM approach to saying what is and isn't spam, but if anyone gets my flier they know it is from me, and they know where to find me. Seco

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ndly, while I drop off multiple fliers at once, it is not really a bulk delivery. The reasons for this are limited by my time and money. Theoretically I coul

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d produce 40,000 fliers and walk the entire city dropping them in peoples letterboxes, but from a practical point of view the cost and the time to do so would

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

be astronomical.

Perhaps a future spamming solution will incorporate the features I have outlined that make turning promotion into spam offline impossible(or

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

at the least non profitable). Cost. Time. Accountability. Any one of these things can go a long way to coming up with a solution to online spamming issues.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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It's always easy to not notice the mundane or subconscious activities we go through each day. However, by observing various aspects of the same genre, or even business, we might be able to enter a whole new market that others have never charted before.

Failure in niche marketing is close to finding out that you have employed the wrong niche research tool. There is nothing shoddier than squandering on money, time, and effort in building up a particular product for your niche market, only to realize in the end that it is not doing any good in the market.

Unless your web content is optimized for search engines, you're losing business hand over fist.

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